Activating Compound | Comment | Organism | Structure |
---|---|---|---|
plasmin | can activate purified enzyme, proteolytic cleavage at Arg92 produces active enzyme, cleavage at Arg330 yields inactive fragments | Homo sapiens | |
thrombin | activation | Homo sapiens | |
Thrombomodulin | proteolytic cleavage at Arg92 produces active enzyme, cleavage at Arg330 yields inactive fragments, activates 1000fold | Homo sapiens | |
Trypsin | can activate purified enzyme, proteolytic cleavage at Arg92 produces active enzyme, cleavage at Arg330 yields inactive fragments | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | synthesized by the liver, released to the plasma, concentration in the latter: 2.5 microgram/ml | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | removal of Lys or Arg from carboxy-terminus of peptides, specific for basic amino acids at carboxy-terminus | Homo sapiens | ? | - |
? |