Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.17.20 extracted from

  • Broze, G.J.
    Thrombin-dependent inhibition of fibrinolysis (1996), Curr. Opin. Hematol., 3, 390-394.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
plasmin can activate purified enzyme, proteolytic cleavage at Arg92 produces active enzyme, cleavage at Arg330 yields inactive fragments Homo sapiens
thrombin activation Homo sapiens
Thrombomodulin proteolytic cleavage at Arg92 produces active enzyme, cleavage at Arg330 yields inactive fragments, activates 1000fold Homo sapiens
Trypsin can activate purified enzyme, proteolytic cleavage at Arg92 produces active enzyme, cleavage at Arg330 yields inactive fragments Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma synthesized by the liver, released to the plasma, concentration in the latter: 2.5 microgram/ml Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information removal of Lys or Arg from carboxy-terminus of peptides, specific for basic amino acids at carboxy-terminus Homo sapiens ?
-
?