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Literature summary for 3.4.17.16 extracted from

  • Hedeager-Sorensen, S.; Kenny, A.J.
    Proteins of the kidney microvillar membrane. Purification and properties of carboxypeptidase P from pig kidneys (1985), Biochem. J., 229, 251-257.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.17.16

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Sus scrofa
EDTA
-
 Sus scrofa
Zn2+ 0.5 mM activates, inhibition above Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1
-
 Benzyloxycarbonyl-Pro-Met
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ MnCl2, 1 mM, is necessary for maximal activity Sus scrofa
Zn each of the two subunits contains one Zn atom, ZnSO4, 0.5 mM, limited activation in absence of MnCl2, strong inhibition above 0.5 mM Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
135000
-
 2 * 135000, pig, SDS-PAGE Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Sus scrofa

Storage Stability

Storage Stability Organism
-20°C, unstable Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Ala-Ala-Ala + H2O
-
 Sus scrofa Ala-Ala-Ala + Ala
-
 ?
Benzyloxycarbonyl-Ala-Phe + H2O
-
 Sus scrofa Benzyloxycarbonyl-Ala + Phe
-
 ?
Benzyloxycarbonyl-Pro-Ala + H2O
-
 Sus scrofa Benzyloxycarbonyl-Pro + Ala
-
 ?
Benzyloxycarbonyl-Pro-Met + H2O
-
 Sus scrofa Benzyloxycarbonyl-Pro + Met
-
 ?
Benzyloxycarbonyl-Pro-Phe + H2O
-
 Sus scrofa Benzyloxycarbonyl-Pro + Phe
-
 ?
Val-Ala-Ala-Phe + H2O
-
 Sus scrofa Val-Ala-Ala + Phe
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 135000, pig, SDS-PAGE Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
20.5
-
 Benzyloxycarbonyl-Pro-Met
-
 Sus scrofa