Application | Comment | Organism |
---|---|---|
medicine | design of mechanism-based, specific inhibitors to cure disease caused by enzyme overfunction | Bos taurus |
Crystallization (Comment) | Organism |
---|---|
structural analysis of enzyme-GlyTyr complexes, design of mechanism-based inactivators based thereon | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-(hydroxyacetyl)-Phe | irreversible inactivation, Kinact/Ki: 71 M-1s-1 | Bos taurus | |
O-(hydroxyacetyl)-beta-phenyllactate | irreversible inactivation, Kinact/Ki: 57 M-1s-1 | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro | mechanism | Bos taurus | |
release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro | evidence of general base pathway | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gly-L-Tyr + H2O | low activity | Bos taurus | Gly + L-Tyr | - |
ir |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Bos taurus |