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Literature summary for 3.4.15.5 extracted from

  • Conlin, C.A.; Miller, C.G.
    Dipeptidyl carboxypeptidase and oligopeptidase A from Escherichia coli and Salmonella typhimurium (1995), Methods Enzymol., 248, 567-579.
    View publication on PubMed
Search for more literature for 3.4.15.5

Cloned(Commentary)

Cloned (Comment) Organism
-
 Salmonella enterica subsp. enterica serovar Typhimurium
-
 Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
captopril
-
 Escherichia coli
captopril
-
 Salmonella enterica subsp. enterica serovar Typhimurium
EDTA
-
 Escherichia coli
EDTA
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ activates Salmonella enterica subsp. enterica serovar Typhimurium
Co2+ activates Escherichia coli
Zinc metallopeptidase Salmonella enterica subsp. enterica serovar Typhimurium
Zinc metallopeptidase Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
77500
-
 E. coli, calculation from nucleotide sequence Escherichia coli
78000
-
 1 * 78000, SDS-PAGE Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Acetyl-Ala3 + H2O Salmonella enterica subsp. enterica serovar Typhimurium the enzyme is required for the utilization of acetyl-Ala3 as a sole nitrogen source ?
-
 ?
Acetyl-Ala3 + H2O Escherichia coli the enzyme is required for the utilization of acetyl-Ala3 as a sole nitrogen source ?
-
 ?
Acetyl-Ala3 + H2O Escherichia coli TN3080 the enzyme is required for the utilization of acetyl-Ala3 as a sole nitrogen source ?
-
 ?
additional information Salmonella enterica subsp. enterica serovar Typhimurium may have an important function in degradation of intracellular proteins ?
-
 ?
additional information Escherichia coli may have an important function in degradation of intracellular proteins ?
-
 ?
additional information Escherichia coli TN3080 may have an important function in degradation of intracellular proteins ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Salmonella enterica subsp. enterica serovar Typhimurium
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Acetyl-Ala-Ala-Ala + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium Acetyl-Ala + Ala-Ala
-
 ?
Acetyl-Ala-Ala-Ala + H2O
-
 Escherichia coli Acetyl-Ala + Ala-Ala
-
 ?
Acetyl-Ala-Ala-Ala + H2O
-
 Escherichia coli TN3080 Acetyl-Ala + Ala-Ala
-
 ?
Acetyl-Ala3 + H2O the enzyme is required for the utilization of acetyl-Ala3 as a sole nitrogen source Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
Acetyl-Ala3 + H2O the enzyme is required for the utilization of acetyl-Ala3 as a sole nitrogen source Escherichia coli ?
-
 ?
Acetyl-Ala3 + H2O the enzyme is required for the utilization of acetyl-Ala3 as a sole nitrogen source Escherichia coli TN3080 ?
-
 ?
additional information enzyme requires a free C terminus, and it cannot hydrolyze bonds in which the peptide nitrogen is donated by proline or in which both amino acids are Gly Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
additional information enzyme requires a free C terminus, and it cannot hydrolyze bonds in which the peptide nitrogen is donated by proline or in which both amino acids are Gly Escherichia coli ?
-
 ?
additional information may have an important function in degradation of intracellular proteins Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
additional information may have an important function in degradation of intracellular proteins Escherichia coli ?
-
 ?
additional information enzyme requires a free C terminus, and it cannot hydrolyze bonds in which the peptide nitrogen is donated by proline or in which both amino acids are Gly Escherichia coli TN3080 ?
-
 ?
additional information may have an important function in degradation of intracellular proteins Escherichia coli TN3080 ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 78000, SDS-PAGE Escherichia coli