Literature summary for 3.4.15.1 extracted from

Kraemer, H.H.; Schmidt, K.; Leis, S.; Schmelz, M.; Sommer, C.; Birklein, F.
Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin (2006), Peptides, 27, 917-920.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	inhibition of angiotensin converting enzyme seems to augment catabolism of calcitonin gene related peptide	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	neutral endopeptidase and angiotensin converting enzyme do not have additive effects regarding neuropeptide degradation	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	neutral endopeptidase and angiotensin converting enzyme do not have additive effects regarding neuropeptide degradation	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)