Literature summary for 3.4.15.1 extracted from

Allard, J.; Buleon, M.; Cellier, E.; Renaud, I.; Pecher, C.; Praddaude, F.; Conti, M.; Tack, I.; Girolami, J.P.
ACE inhibitor reduces growth factor receptor expression and signaling but also albuminuria through B2-kinin glomerular receptor activation in diabetic rats (2007), Am. J. Physiol. Renal Physiol., 293, F1083-F1092.

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Application

Application	Comment	Organism
medicine	in the early phase of diabetes, the angiotensin-converting enzyme inhibitorramipril reverses glomerular overexpression and activation of some critical growth factor pathways and increases protection against oxidative stress. These effects involve B2-kinin receptor activation	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
ramipril	in the early phase of diabetes, the angiotensin-converting enzyme inhibitor reverses glomerular overexpression and activation of some critical growth factor pathways and increases protection against oxidative stress. These effects involve B2-kinin receptor activation	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

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Release 2023.1 (January 2023)