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Literature summary for 3.4.14.9 extracted from

  • Kyttaelae, A.; Lahtinen, U.; Braulke, T.; Hofmann, S.L.
    Functional biology of the neuronal ceroid lipofuscinoses (NCL) proteins (2006), Biochim. Biophys. Acta, 1762, 920-933.
    View publication on PubMed
Search for more literature for 3.4.14.9

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
 mature protein, SDS-PAGE Homo sapiens
66000
-
 immature protein, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein TPP 1 is glycosylatd at most or all of five asparagin-linked glycosylation sites Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Cholecystokinin + H2O
-
 Homo sapiens ?
-
 ?
additional information prefers Leu, Phe and Nle at the P1 position, whereas Asn, His, Lys, Arg, Ser, Val, Ile, Thr, Gly and Pro are highly unfavored in this position, showing less than 1% of the activity of the best substrates Homo sapiens ?
-
 ?
Neuromedin B + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
TPP I prefers Leu, Phe and Nle at the P1 position, whereas Asn, His, Lys, Arg, Ser, Val, Ile, Thr, Gly and Pro are highly unfavored in this position, showing less than 1% of the activity of the best substrates Homo sapiens
tripeptidyl peptidase-I
-
 Homo sapiens

pH Stability

pH Stability pH Stability Maximum Comment Organism
3
-
 has weak endoproteolytic activity at pH 3 Homo sapiens