Application | Comment | Organism |
---|---|---|
analysis | significant levels of enzyme activity are present in commercial human serum albumin. This activity is abolished using a specific DPP-IV inhibitor. Fully 70 to 80% DPP-IV activity remains at 60°C compared with the 37°C incubate. No DPP-IV activity is present in recombinant human serum albumin, suggesting that DPP-IV activity is present only in serum albumin produced using the Cohn fractionation process. DPP-IV activity contributes to the formation of aspartate-alanine diketopiperazine, a known immunomodulatory molecule from the N terminus of human albumin, could account for some of the clinical effects of commercial human serum albumin | Homo sapiens |
medicine | significant levels of enzyme activity are present in commercial human serum albumin. This activity is abolished using a specific DPP-IV inhibitor. Fully 70 to 80% DPP-IV activity remains at 60°C compared with the 37°C incubate. No DPP-IV activity is present in recombinant human serum albumin, suggesting that DPP-IV activity is present only in serum albumin produced using the Cohn fractionation process. DPP-IV activity contributes to the formation of aspartate-alanine diketopiperazine, a known immunomodulatory molecule from the N terminus of human albumin, could account for some of the clinical effects of commercial human serum albumin | Homo sapiens |
Organism | UniProt | Comment | Textmining |
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Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | commercial solution of human serum albumin | Homo sapiens | - |