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Literature summary for 3.4.14.5 extracted from
- Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine (2009), J. Enzyme Inhib. Med. Chem., 24, 1061-1066.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Berberine | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P27487 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Gly-L-Pro-4-nitroanilide + H2O | - |
Homo sapiens | Gly-L-Pro + 4-nitroaniline | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| dipeptidyl peptidase IV | - |
Homo sapiens |
| DPP IV | - |
Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0133 | - |
in Tris buffer (pH 7.5, 50 mM), at 37°C | Homo sapiens | Berberine | |
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