Literature summary for 3.4.14.5 extracted from

Tsu, H.; Chen, X.; Chen, C.T.; Lee, S.J.; Chang, C.N.; Kao, K.H.; Coumar, M.S.; Yeh, Y.T.; Chien, C.H.; Wang, H.S.; Lin, K.T.; Chang, Y.Y.; Wu, S.H.; Chen, Y.S.; Lu, I.L.; Wu, S.Y.; Tsai, T.Y.; Chen, W.C.; Hsieh, H.P.; Chao, Y.S.; Jiaang, W.T.
2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV (2006), J. Med. Chem., 49, 373-380.

Inhibitors

Inhibitors	Comment	Organism	Structure
1-[3-[2-[2-cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-1-oxopropyl]-4-[benzothiazol-2-yl]piperazine	-	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms	Comment	Organism
DPP-IV	-	Homo sapiens

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.000527	-	-	Homo sapiens	1-[3-[2-[2-cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-1-oxopropyl]-4-[benzothiazol-2-yl]piperazine

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)