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Literature summary for 3.4.14.5 extracted from

  • He, Y.L.; Sabo, R.; Sunkara, G.; Bizot, M.N.; Riviere, G.J.; Leon, S.; Ligueros-Saylan, M.; Dole, W.P.; Howard, D.
    Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers (2007), J. Clin. Pharmacol., 47, 998-1004.
    View publication on PubMed

Application

Application Comment Organism
medicine vildagliptin is a novel antidiabetic agent that is an orally active, potent, and selective inhibitor of dipeptidyl peptidase IV, the enzyme responsible for degradation of the incretin hormones. No dose adjustment is necessary when vildagliptin and digoxin are coadministered Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
vildagliptin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-