Application | Comment | Organism |
---|---|---|
medicine | inhibition of dipeptidylpeptidase IV activity as a therapy of type 2 diabetes | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide-1 + H2O | Homo sapiens | dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect | ? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | Homo sapiens | dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Homo sapiens | - |
biliary duct | - |
Homo sapiens | - |
brain | endothelium | Homo sapiens | - |
endothelium | of spleen, lung, brain and vessels supplying the liver | Homo sapiens | - |
gastrointestinal tract | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
lung | endothelium | Homo sapiens | - |
lymph node | - |
Homo sapiens | - |
mammary gland | - |
Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
prostate | - |
Homo sapiens | - |
salivary gland | - |
Homo sapiens | - |
spleen | endothelium | Homo sapiens | - |
sweat gland | - |
Homo sapiens | - |
thymus | - |
Homo sapiens | - |
uterus | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha1-microglobulin + H2O | - |
Homo sapiens | ? | - |
? | |
aprotinin + H2O | - |
Homo sapiens | ? | - |
? | |
beta-casomorphin + H2O | - |
Homo sapiens | ? | - |
? | |
corticotropin-like intermediate lobe peptide + H2O | - |
Homo sapiens | ? | - |
? | |
enterostatin + H2O | - |
Rattus norvegicus | ? | - |
? | |
gastrin-releasing peptide + H2O | - |
Homo sapiens | ? | - |
? | |
glucagon-like peptide-1 + H2O | - |
Homo sapiens | ? | - |
? | |
glucagon-like peptide-1 + H2O | dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect | Homo sapiens | ? | - |
? | |
glucagon-like peptide-2 + H2O | - |
Mus musculus | ? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | - |
Homo sapiens | ? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect | Homo sapiens | ? | - |
? | |
growth hormone-releasing hormone + H2O | - |
Homo sapiens | ? | - |
? | |
procolipase + H2O | - |
Homo sapiens | ? | - |
? | |
prolactin + H2O | - |
Homo sapiens | ? | - |
? | |
Substance P + H2O | - |
Homo sapiens | ? | - |
? | |
trypsinogen propeptide + H2O | - |
Homo sapiens | ? | - |
? | |
Tyr-melanostatin + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dipeptidylpeptidase IV | - |
Mus musculus |
dipeptidylpeptidase IV | - |
Homo sapiens |
dipeptidylpeptidase IV | - |
Rattus norvegicus |
DPP IV | - |
Mus musculus |
DPP IV | - |
Homo sapiens |
DPP IV | - |
Rattus norvegicus |