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Literature summary for 3.4.14.5 extracted from
- Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27(kip1) enhancement, and disruption of binding to the extra (2006), Clin. Cancer Res., 12, 3470-3477.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | CD26 is an appropriate molecular target for renal cell carcinoma therapy. Anti-CD26 mAb treatment leads to loss of tumorigenicity. The potent antitumor effect of anti-CD26 mAb may be used in the future as novel therapeutic approaches against various CD26-positive malignancies, including renal cell carcinoma | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
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- |
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Release 2023.1 (January 2023)
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