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Literature summary for 3.4.14.1 extracted from
- Calcium entry into keratinocytes induces exocytosis of lysosomes (2004), Arch. Dermatol. Res., 296, 30-41.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Homo sapiens | 5764 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| culture medium | very low cathepsin C activity in culture medium of untreated keratinocytes, suggesting that the constitutive exocytosis of lysosomes is weak in keratinocytes. Treatment with 0.03 mM ionomycin for 50 min induces the release of about 20% of cathepsin C activity. Incubation of keratinocytes for 30 min with 1 mM calcium and 0.01 mM ionomycin causes a significant release of cathepsin C activity | Homo sapiens | - |
| keratinocyte | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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