Cloned (Comment) | Organism |
---|---|
- |
Deinococcus radiodurans |
Crystallization (Comment) | Organism |
---|---|
to 1.4 A resolution. XPP forms a dimeric structure via unique dimer stabilization loops of N-terminal domains such that their C-terminal domains are placed far apart from each other | Deinococcus radiodurans |
Protein Variants | Comment | Organism |
---|---|---|
R46A | two orders of magnitude loss in the enzymatic activity for all the dipeptides attempted. The Glu340 side-chain interacts with Arg46 and stabilizes its side-chain conformation that is appropriate for substrate binding | Deinococcus radiodurans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.3 | - |
Phe-Pro | pH 8.0, 55°C | Deinococcus radiodurans | |
1.5 | - |
Lys-Pro | pH 8.0, 55°C | Deinococcus radiodurans | |
1.7 | - |
Met-Pro | pH 8.0, 55°C | Deinococcus radiodurans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | presence of 1 mM in the assay | Deinococcus radiodurans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Deinococcus radiodurans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Lys-Pro + H2O | - |
Deinococcus radiodurans | Lys + Pro | - |
? | |
Met-Pro + H2O | - |
Deinococcus radiodurans | Met + Pro | - |
? | |
additional information | the decreasing order of preference for the P1 residue in the Xaa-Pro dipeptides is Ala, Ser, Phe=Lys, Met, Leu, Gly, Arg, Pro, Val, Tyr, Ile, His, Asp | Deinococcus radiodurans | ? | - |
? | |
Phe-Pro + H2O | - |
Deinococcus radiodurans | Phe + Pro | - |
? |
Synonyms | Comment | Organism |
---|---|---|
XPP | - |
Deinococcus radiodurans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
178 | - |
Met-Pro | pH 8.0, 55°C | Deinococcus radiodurans | |
256 | - |
Phe-Pro | pH 8.0, 55°C | Deinococcus radiodurans | |
349 | - |
Lys-Pro | pH 8.0, 55°C | Deinococcus radiodurans |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
102 | - |
Met-Pro | pH 8.0, 55°C | Deinococcus radiodurans | |
201 | - |
Phe-Pro | pH 8.0, 55°C | Deinococcus radiodurans | |
233 | - |
Lys-Pro | pH 8.0, 55°C | Deinococcus radiodurans |