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BRENDA support

Literature summary for 3.4.11.9 extracted from

  • La Corte, A.L.; Carter, A.M.; Turner, A.J.; Grant, P.J.; Hooper, N.M.
    The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill (2008), J. Renin Angiotensin Aldosterone Syst., 9, 221-225.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information women on the oral contraceptive pill have higher age-adjusted plasma AP-P compared to women not on the oral contraceptive pill or males Homo sapiens
progesterone exposure of HepG2 cells to 0.001 mM progesterone results in a significant increase in the AP-P activity of cell lysates Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-
Hep-G2 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bradykinin + H2O
-
Homo sapiens L-Arg + des-Arg-bradykinin
-
?

Synonyms

Synonyms Comment Organism
aminopeptidase P
-
Homo sapiens
AP-P
-
Homo sapiens