Cloned (Comment) | Organism |
---|---|
- |
Mycoplasma hyopneumoniae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bestatin | 1 mM, 13% residual activity | Mycoplasma hyopneumoniae | |
Cu2+ | 5 mM, 3.5% residual activiy | Mycoplasma hyopneumoniae | |
EDTA | 10 mM, 3.7% residual activiy | Mycoplasma hyopneumoniae | |
Mn2+ | 5 mM, 15% residual activiy | Mycoplasma hyopneumoniae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | enzyme resides in the cytosol, but a subset of molecules are both bound to and secreted from the cell surface | Mycoplasma hyopneumoniae | 9986 | - |
cytosol | enzyme resides in the cytosol, but a subset of molecules are both bound to and secreted from the cell surface | Mycoplasma hyopneumoniae | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | 5 mM, 52% activation | Mycoplasma hyopneumoniae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
39200 | - |
12 * 39200, calculated, 12 * 40000, SDS-PAGE | Mycoplasma hyopneumoniae |
40000 | - |
12 * 39200, calculated, 12 * 40000, SDS-PAGE | Mycoplasma hyopneumoniae |
440000 | - |
gel filtration | Mycoplasma hyopneumoniae |
600000 | - |
PAGE | Mycoplasma hyopneumoniae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycoplasma hyopneumoniae | Q4AAK4 | - |
- |
Mycoplasma hyopneumoniae ATCC 25934 | Q4AAK4 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ala-4-methylcoumaryl-7-amide + H2O | about 50% of the activity with L-Glu-4-methylcoumaryl-7-amide | Mycoplasma hyopneumoniae | L-Ala + 7-amino-4-methylcoumarin | - |
? | |
L-Ala-4-methylcoumaryl-7-amide + H2O | about 50% of the activity with L-Glu-4-methylcoumaryl-7-amide | Mycoplasma hyopneumoniae ATCC 25934 | L-Ala + 7-amino-4-methylcoumarin | - |
? | |
L-Glu-4-methylcoumaryl-7-amide + H2O | - |
Mycoplasma hyopneumoniae | L-Glu + 7-amino-4-methylcoumarin | - |
? | |
L-Glu-4-methylcoumaryl-7-amide + H2O | - |
Mycoplasma hyopneumoniae ATCC 25934 | L-Glu + 7-amino-4-methylcoumarin | - |
? | |
L-Leu-4-methylcoumaryl-7-amide + H2O | - |
Mycoplasma hyopneumoniae | L-Leu + 7-amino-4-methylcoumarin | about 20% of the activity with L-Glu-4-methylcoumaryl-7-amide | ? | |
L-Leu-4-methylcoumaryl-7-amide + H2O | - |
Mycoplasma hyopneumoniae ATCC 25934 | L-Leu + 7-amino-4-methylcoumarin | about 20% of the activity with L-Glu-4-methylcoumaryl-7-amide | ? |
Subunits | Comment | Organism |
---|---|---|
dodecamer | 12 * 39200, calculated, 12 * 40000, SDS-PAGE | Mycoplasma hyopneumoniae |
Synonyms | Comment | Organism |
---|---|---|
MHJ_0125 | - |
Mycoplasma hyopneumoniae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Mycoplasma hyopneumoniae |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Mycoplasma hyopneumoniae | calculated | - |
6.2 |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme acts as a multifunctional adhesin, binding to both heparin and plasminogen. It binds plasminogen and facilitates its activation by tissue plasminogen activator. Plasmin cleaves host extracellular matrix proteins and activates matrix metalloproteases, generating peptide substrates for the enzyme and a source of amino acids for growth of Mycoplasma hyopneumoniae | Mycoplasma hyopneumoniae |