Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.11.7 extracted from

  • Georgiadis, D.; Vazeux, G.; Llorens-Cortes, C.; Yiotakis, A.; Dive, V.
    Potent and selective inhibition of zinc aminopeptidase A (EC 3.4.11.7, APA) by glutamyl aminophosphinic peptides: importance of glutamyl aminophosphinic residue in the P1 position (2000), Biochemistry, 39, 1152-1155.
    View publication on PubMed
Search for more literature for 3.4.11.7

Inhibitors

Inhibitors Comment Organism Structure
Ala-PSI[PO2-CH2]-Leu-Ala
-
 Mus musculus
Glu-PSI[PO2-CH2]-Leu
-
 Mus musculus
Glu-PSI[PO2-CH2]-Leu-Ala
-
 Mus musculus
Glu-PSI[PO2-CH2]-Leu-Arg
-
 Mus musculus
Glu-PSI[PO2-CH2]-Leu-Asp
-
 Mus musculus
Glu-PSI[PO2-CH2]-Leu-Leu
-
 Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 alpha-L-Glu-beta-naphthylamide pH 7.4, 25°C Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus P16406
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-L-Glu-beta-naphthylamide + H2O
-
 Mus musculus L-Glu + 2-naphthylamine
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0000008
-
 Glu-PSI[PO2-CH2]-Leu-Ala pH 7.4, 25°C Mus musculus
0.0000009
-
 Ala-PSI[PO2-CH2]-Leu-Ala pH 7.4, 25°C Mus musculus
0.0000057
-
 Glu-PSI[PO2-CH2]-Leu-Asp pH 7.4, 25°C Mus musculus
0.00003
-
 Glu-PSI[PO2-CH2]-Leu-Arg pH 7.4, 25°C Mus musculus
0.000037
-
 Glu-PSI[PO2-CH2]-Leu-Leu pH 7.4, 25°C Mus musculus
0.000194
-
 Glu-PSI[PO2-CH2]-Leu pH 7.4, 25°C Mus musculus