Literature summary for 3.4.11.6 extracted from

Mantle, D.; Lauffart, B.; Pennington, R.J.T.
Purification and partial characterization of arginine aminopeptidases from human skeletal muscle (1984), Biochem. Soc. Trans., 12, 826-827.

No PubMed abstract available

Search for more literature for 3.4.11.6

Inhibitors

Inhibitors	Comment	Organism	Structure
bestatin	-	Homo sapiens
EDTA	-	Homo sapiens
p-Hydroxymercuriphenylsulfonic acid	-	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.07	-	arginyl-4-methylcoumarin 7-amide	enzyme I	Homo sapiens
0.27	-	arginyl-4-methylcoumarin 7-amide	enzyme II	Homo sapiens
0.28	-	lysyl-4-methylcoumarin 7-amide	enzyme I	Homo sapiens
0.4	-	lysyl-4-methylcoumarin 7-amide	enzyme II	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Br-	activation	Homo sapiens
Cl-	required for activity	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
72000	75000	gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
2 forms	Homo sapiens

Storage Stability

Storage Stability	Organism
6°C, 6 d	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Arg-4-methylcoumarin 7-amide + H2O	-	Homo sapiens	Arg + 7-amino-4-methylcoumarin	-	?
Arg-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	Arg + 7-amino-4-methylcoumarin	-	?
Lys-4-methylcoumarin 7-amide + H2O	-	Homo sapiens	Lys + 7-amino-4-methylcoumarin	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6.5	-	-	Homo sapiens

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Release 2023.1 (January 2023)