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Literature summary for 3.4.11.22 extracted from

  • York, I.A.; Brehm, M.A.; Zendzian, S.; Towne, C.F.; Rock, K.L.
    Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance (2006), Proc. Natl. Acad. Sci. USA, 103, 9202-9207.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.11.22

Cloned(Commentary)

Cloned (Comment) Organism
-
 Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information generation of ERAP1-knockout mice, which show a shift in the hierarchy of immunodominance in viral infections, even when the responding T-cells have the same T-cell receptor repertoire, mutant immunodominance hierarchy: GP276, NP396, GP33, GP34, GP118, NP205, CD8+ T-cell responses to viral epitopes are altered in transgenic mice, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Mus musculus 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus ERAP1 trims MHC class I-presented peptides in vivo and plays an important role in immunodominance, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57/BL6 mice, isozyme ERAP1
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Mus musculus
-
splenocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ERAP1 trims MHC class I-presented peptides in vivo and plays an important role in immunodominance, overview Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
endoplasmic reticulum aminopeptidase 1
-
 Mus musculus
ER aminopeptidase 1
-
 Mus musculus
ERAP1
-
 Mus musculus