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Literature summary for 3.4.11.2 extracted from

  • Roecken, C.; Licht, J.; Roessner, A.; Carl-McGrath, S.
    Canalicular immunostaining of aminopeptidase N (CD13) as a diagnostic marker for hepatocellular carcinoma (2005), J. Clin. Pathol., 58, 1069-1075.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
diagnostics aminopeptidase N is a diagnostic marker for hepatocellular carcinoma using canalicular immunostaining Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane apical, enzyme content in non-canalicular and canalicular cell membranes Homo sapiens 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is involved in postsecretory processing of neuropeptides and peptide hormones ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
hepatocellular carcinoma cell neoplastic lievre tissue, canalicular pattern of the enzyme, overview Homo sapiens
-
liver healthy, expression pattern of the enzyme, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in postsecretory processing of neuropeptides and peptide hormones Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
aminopeptidase N
-
Homo sapiens
CD13
-
Homo sapiens