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Literature summary for 3.4.11.2 extracted from

  • Bernkop-Schnurch, A.; Zarti, H.; Walker, G.F.
    Thiolation of polycarbophil enhances its inhibition of intestinal brush border membrane bound aminopeptidase N (2001), J. Pharm. Sci., 90, 1907-1914.
    View publication on PubMed
Search for more literature for 3.4.11.2

Inhibitors

Inhibitors Comment Organism Structure
cysteine
-
 Sus scrofa
additional information
-
 Sus scrofa
polycarbophil
-
 Sus scrofa
polycarbophil-cysteine conjugates cysteine linked to polycarbophil by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride, strong inhibitor, protects leucine enkephalin against degradation by the enzyme Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
brush border
-
 Sus scrofa 5903
-
membrane
-
 Sus scrofa 16020
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestinal mucosa
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Leu-4-nitroanilide + H2O synthetic substrate Sus scrofa L-Leu + 4-nitroaniline
-
 ?
leucine enkephalin + H2O model peptide drug Sus scrofa ?
-
 ?

Synonyms

Synonyms Comment Organism
aminopeptidase N
-
 Sus scrofa