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Literature summary for 3.4.11.18 extracted from
- Team work in protein processing (2007), Chem. Biol., 14, 732-734.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| bengamide A | nonspecific, reversible inhibitor of MetAP-1 and MetAP-2; nonspecific, reversible inhibitor of MetAP-1 and MetAP-2 | Homo sapiens |  |
| IV-43 | reversible MetAP-1 inhibitor | Homo sapiens | |
| TNP-470 | selective covalent MetAP-2 inhibitor | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P50579 | - |
- |
| Homo sapiens | P53582 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| proto-oncogene c-Src + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MetAP-1 | - |
Homo sapiens |
| MetAP-2 | - |
Homo sapiens |
| methionine aminopeptidase type 1 | - |
Homo sapiens |
| methionine aminopeptidase type 2 | - |
Homo sapiens |
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