Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.11.14 extracted from

  • Little, G.H.; Starnes, W.L.; Behal, F.J.
    Human liver aminopeptidase (1976), Methods Enzymol., 45, 495-503.
    View publication on PubMed
Search for more literature for 3.4.11.14

Inhibitors

Inhibitors Comment Organism Structure
benzylpenicillenic acid
-
 Homo sapiens
penicillin
-
 Homo sapiens
puromycin
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ 2.4fold activation, Co2+ binds loosely in a noncompetitive manner Homo sapiens
Zinc 8.3 nanoatoms of tightly bound zinc per mg of protein Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
120000
-
 2 * 120000, SDS-PAGE Homo sapiens
223000
-
 sedimentation equilibrium centrifugation Homo sapiens
242000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein contains 17.5% carbohydrate - 4.3% glucosamine, 4.1% sialic acid, 9% hexoses Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-2-naphthylamide + H2O
-
 Homo sapiens Ala + 2-naphthylamine
-
 ?
Ala-Ala + H2O 45.4% of the activity with Ala-Trp Homo sapiens Ala + Ala
-
 ?
Ala-Asp + H2O 11.4% of the activity with Ala-Trp Homo sapiens Ala + Asp
-
 ?
Ala-Glu + H2O 19.0% of the activity with Ala-Trp Homo sapiens Ala + Glu
-
 ?
Ala-Gly + H2O 17.8% of the activity with Ala-Trp Homo sapiens Ala + Gly
-
 ?
Ala-Leu + H2O 27.1% of the activity with Ala-Trp Homo sapiens Ala + Leu
-
 ?
Ala-Phe + H2O 42.8% of the activity with Ala-Trp Homo sapiens Ala + Phe
-
 ?
Ala-Ser + H2O 22.5% of the activity with Ala-Trp Homo sapiens Ala + Ser
-
 ?
Ala-Trp + H2O
-
 Homo sapiens Ala + Trp
-
 ?
Ala-Val + H2O 47.3% of the activity with Ala-Trp Homo sapiens Ala + Val
-
 ?
Arg-2-naphthylamide + H2O 28% of the activity with Ala-2-naphthylamide Homo sapiens Arg + 2-naphthylamine
-
 ?
Gly-2-naphthylamide + H2O 13.7% of the activity with Ala-2-naphthylamide Homo sapiens Gly + 2-naphthylamine
-
 ?
Leu-2-naphthylamide + H2O 36.4% of the activity with Ala-2-naphthylamide Homo sapiens Leu + 2-naphthylamine
-
 ?
Leu-Ala + H2O 25.6% of the activity with Ala-Trp Homo sapiens Leu + Ala
-
 ?
Leu-Gly + H2O 5.5% of the activity with Ala-Trp Homo sapiens Leu + Gly
-
 ?
Leu-Leu + H2O 35.9% of the activity with Ala-Trp Homo sapiens Leu + Leu
-
 ?
Lys-2-naphthylamide + H2O 13.4% of the activity with Ala-2-naphthylamide Homo sapiens Lys + 2-naphthylamine
-
 ?
Met-2-naphthylamide + H2O 57.5% of the activity with Ala-2-naphthylamide Homo sapiens Met + 2-naphthylamine
-
 ?
Phe-2-naphthylamide + H2O 62.8% of the activity with Ala-2-naphthylamide Homo sapiens Phe + 2-naphthylamine
-
 ?
Phe-Gly + H2O 19.2% of the activity with Ala-Trp Homo sapiens Phe + Gly
-
 ?
Ser-2-naphthylamide + H2O 6.0% of the activity with Ala-2-naphthylamide Homo sapiens Ser + 2-naphthylamine
-
 ?
Thr-2-naphthylamide + H2O 5.7% of the activity with Ala-2-naphthylamide Homo sapiens Thr + 2-naphthylamine
-
 ?
Trp-2-naphthylamide + H2O 19.2% of the activity with Ala-2-naphthylamide Homo sapiens Trp + 2-naphthylamine
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 120000, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
-
 Homo sapiens