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Literature summary for 3.4.11.10 extracted from

  • Ustynyuk, L.; Bennett, B.; Edwards, T.; Holz, R.C.
    Inhibition of the aminopeptidase from Aeromonas proteolytica by aliphatic alcohols. Characterization of the hydrophobic substrate recognition site (1999), Biochemistry, 38, 11433-11439.
    View publication on PubMed
Search for more literature for 3.4.11.10

General Stability

General Stability Organism
not denatured in aliphatic alcohols up to 20% concentration Vibrio proteolyticus

Inhibitors

Inhibitors Comment Organism Structure
2-propanol Ki: 8 mM Vibrio proteolyticus
3-methyl-1-butanol Ki: 0.98 mM Vibrio proteolyticus
benzyl alcohol Ki: 2.6 mM Vibrio proteolyticus
ethanol Ki: 80 mM Vibrio proteolyticus
methanol Ki: 860 mM Vibrio proteolyticus
n-butanol Ki: 2.7 mM Vibrio proteolyticus
n-Propanol Ki: 11 mM Vibrio proteolyticus
phenol Ki: 4 mM Vibrio proteolyticus
tert-butanol Ki: 10 mM Vibrio proteolyticus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Peptides + H2O Vibrio proteolyticus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Vibrio proteolyticus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Peptides + H2O
-
 Vibrio proteolyticus ?
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.98
-
 3-methyl-1-butanol
-
 Vibrio proteolyticus
2.6
-
 benzyl alcohol
-
 Vibrio proteolyticus
2.7
-
 n-butanol
-
 Vibrio proteolyticus
4
-
 phenol
-
 Vibrio proteolyticus
8
-
 2-propanol
-
 Vibrio proteolyticus
10
-
 tert-butanol
-
 Vibrio proteolyticus
11
-
 n-Propanol
-
 Vibrio proteolyticus
80
-
 ethanol
-
 Vibrio proteolyticus