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Literature summary for 3.3.2.9 extracted from
- Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma (2007), Thorax, 62, 1050-1057.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | high EPHX1 activity is associated with an increased risk for lifetime asthma, which varies by glutathione S-transferase P1 Ile105Val genotype and by residential proximity to major roads. Among children with glutathione S-transferase P1 105Val/Val genotype, those who have high EPHX1 phenotype have a fourfold increased risk of lifetime asthma. Among children living within 75 metres of a major road, those with high EPHX1 activity had a 3.2-fold higher lifetime asthma risk. The results are similar for current, early persistent and late onset asthma | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
isoform EPHX1, children with asthma | - |
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Release 2023.1 (January 2023)
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