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Literature summary for 3.3.2.9 extracted from

  • Lu, A.Y.H.; Levin, W.
    Purification and assay of liver microsomal epoxide hydrase (1978), Methods Enzymol., 52, 193-200.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
1-(2-Isopropylphenyl)-imidazole stimulates Rattus norvegicus
Metyrapone stimulates Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Emulgen 911 0.1%, 53% inhibition Rattus norvegicus
iodoacetamide
-
Rattus norvegicus
p-hydroxymercuribenzoate
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.596
-
-
Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-methylcholanthrene 11,12-oxide + H2O
-
Rattus norvegicus ?
-
?
benzoanthracene 5,6-oxide + H2O
-
Rattus norvegicus ?
-
?
benzopyrene 11,12-oxide + H2O
-
Rattus norvegicus ?
-
?
benzopyrene 4,5-oxide + H2O
-
Rattus norvegicus (-)benzopyrene 4,5-dihydrodiol
-
?
benzopyrene 7,8-oxide + H2O
-
Rattus norvegicus ?
-
?
benzopyrene 9,10-oxide + H2O
-
Rattus norvegicus ?
-
?
dibenzanthracene 5,6-oxide + H2O
-
Rattus norvegicus ?
-
?
naphthalene-1,2-oxide + H2O
-
Rattus norvegicus ?
-
?
octene 1,2-oxide + H2O
-
Rattus norvegicus ?
-
?
phenanthrene-9,10-oxide + H2O
-
Rattus norvegicus ?
-
?
styrene 7,8-oxide + H2O
-
Rattus norvegicus styrene glycol
-
?
styrene oxide + H2O
-
Rattus norvegicus styrene glycol
-
?