Literature summary for 3.3.2.6 extracted from

Thunnissen, M.M.G.M.; Nordlund, P.; Haeggstrom, J.Z.
Crystal structure of human leukotriene A4 hydrolase, a bifunctional enzyme in inflammation (2001), Nat. Struct. Biol., 8, 131-135.

Search for more literature for 3.3.2.6

Application

Application	Comment	Organism
medicine	the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structure of enzyme complexed with bestatin	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zinc	zinc protein	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
leukotriene A4 + H2O	Homo sapiens	biosynthesis of leukotriene B4	leukotriene B4	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P09960	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
leukotriene A4 + H2O	-	Homo sapiens	leukotriene B4	-	?
leukotriene A4 + H2O	biosynthesis of leukotriene B4	Homo sapiens	leukotriene B4	-	?

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Release 2023.1 (January 2023)