Literature summary for 3.3.2.10 extracted from

Nayeem, M.A.; Zeldin, D.C.; Boegehold, M.A.; Falck, J.R.
Salt modulates vascular response through adenosine A(2A) receptor in eNOS-null mice: role of CYP450 epoxygenase and soluble epoxide hydrolase (2011), Mol. Cell. Biochem., 350, 101-111.

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Application

Application	Comment	Organism
medicine	study on the mechanism behind adenosine-induced vascular response in high salt-fed eNOS+/+ and eNOS-/- mice. Compared to low salt diet, high salt diet increases CYP2J2 in eNOS+/+ and eNOS-/- mice, but decreases sEH in eNOS+/+ and eNOS-/- animals. Similarly, CYP4A decreases in high salt-fed-eNOS+/+ and -eNOS-/- animals. Data suggest that low salt diet causes reduced-vasodilation in both eNOS+/+ and eNOS-/- background via sEH and CYP4A	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

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Release 2023.1 (January 2023)