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Literature summary for 3.3.2.10 extracted from

  • Li, N.; Liu, J.Y.; Timofeyev, V.; Qiu, H.; Hwang, S.H.; Tuteja, D.; Lu, L.; Yang, J.; Mochida, H.; Low, R.; Hammock, B.D.; Chiamvimonvat, N.
    Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches (2009), J. Mol. Cell. Cardiol., 47, 835-845.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.3.2.10

Inhibitors

Inhibitors Comment Organism Structure
1-adamantan-1-yl-3-{5-[2-(2-ethoxy-ethoxy)-ethoxy]-pentyl}-urea i.e. AEPU, shows beneficial effects in cardiac hypertrophy, evaluation in a clinically relevant murine model of myocardial infarction, overview Mus musculus
trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid i.e. tAUCB, shows beneficial effects in cardiac hypertrophy, evaluation in a clinically relevant murine model of myocardial infarction, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus sEH catalyzes the conversion of epoxyeicosatrienoic acids, EETs, to form the corresponding dihydroxyeicosatrienoic acids, DHETs ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P34914 male C57BL/6J mice
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information clinically relevant murine model of myocardial infarction Mus musculus
-
myocardium
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information sEH catalyzes the conversion of epoxyeicosatrienoic acids, EETs, to form the corresponding dihydroxyeicosatrienoic acids, DHETs Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
SEH
-
 Mus musculus

General Information

General Information Comment Organism
malfunction beneficial effects of several potent soluble epoxide hydrolase inhibitors in cardiac hypertrophy Mus musculus