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Literature summary for 3.3.2.10 extracted from

  • Chaudhary, K.R.; Abukhashim, M.; Hwang, S.H.; Hammock, B.D.; Seubert, J.M.
    Inhibition of soluble epoxide hydrolase by trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury (2010), J. Cardiovasc. Pharmacol., 55, 67-73.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.3.2.10

Inhibitors

Inhibitors Comment Organism Structure
trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid i.e. t-AUCB, causes enzyme inhibition that is protective against ischemia-reperfusion injury, reversible by 14,15-epoxyeicosatrienoic acid, mechanisms, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(5Z,8Z,11Z)-14,15-epoxyeicosatrienoic acid + H2O Mus musculus
-
 (5Z,8Z,11Z)-14,15-dihydroxyeicosatrienoic acid
-
 ?
(5Z,8Z,11Z)-14,15-epoxyeicosatrienoic acid + H2O Mus musculus C57BL6
-
 (5Z,8Z,11Z)-14,15-dihydroxyeicosatrienoic acid
-
 ?
(5Z,8Z,14Z)-11,12-epoxyeicosatrienoic acid + H2O Mus musculus
-
 (5Z,8Z,14Z)-11,12-dihydroxyeicosatrienoic acid
-
 ?
(5Z,8Z,14Z)-11,12-epoxyeicosatrienoic acid + H2O Mus musculus C57BL6
-
 (5Z,8Z,14Z)-11,12-dihydroxyeicosatrienoic acid
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P34914 C57Bl6 mice
-
Mus musculus C57BL6 P34914 C57Bl6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(5Z,8Z,11Z)-14,15-epoxyeicosatrienoic acid + H2O
-
 Mus musculus (5Z,8Z,11Z)-14,15-dihydroxyeicosatrienoic acid
-
 ?
(5Z,8Z,11Z)-14,15-epoxyeicosatrienoic acid + H2O
-
 Mus musculus C57BL6 (5Z,8Z,11Z)-14,15-dihydroxyeicosatrienoic acid
-
 ?
(5Z,8Z,14Z)-11,12-epoxyeicosatrienoic acid + H2O
-
 Mus musculus (5Z,8Z,14Z)-11,12-dihydroxyeicosatrienoic acid
-
 ?
(5Z,8Z,14Z)-11,12-epoxyeicosatrienoic acid + H2O
-
 Mus musculus C57BL6 (5Z,8Z,14Z)-11,12-dihydroxyeicosatrienoic acid
-
 ?

Synonyms

Synonyms Comment Organism
SEH
-
 Mus musculus