Activating Compound | Comment | Organism | Structure |
---|---|---|---|
1-Benzylimidazole | activates mirosomal activity with styrene oxide as substrate | Homo sapiens | |
benzil | - |
Rattus norvegicus | |
benzil | activates mirosomal activity with styrene oxide as substrate | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-Benzylimidazole | microsomal activity with cis-stilbene oxide as substrate | Homo sapiens | |
1-trichloropropene oxide | - |
Homo sapiens | |
benzil | inhibition of microsomal enzyme with cis-stilbene oxide, and of cytosolic enzyme forms cEHTSO and cEHCSO | Homo sapiens | |
chalcone | microsomal activity with cis-stilbene oxide as substrate, cytosolic enzyme form cEHCSO and cEHTSO | Homo sapiens | |
styrene oxide | - |
Homo sapiens | |
styrene oxide | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0017 | - |
trans-stilbene oxide | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
cytosol | - |
Rattus norvegicus | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49000 | - |
x * 49000, SDS-PAGE | Homo sapiens |
49000 | - |
x * 49000, SDS-PAGE | Rattus norvegicus |
60000 | - |
2 * 60000, SDS-PAGE | Rattus norvegicus |
120000 | - |
gel filtration | Rattus norvegicus |
130000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
2 cytosolic enzyme forms: 1. cEHTSO, epoxide hydrolase with diagnostic substrate specificity for trans-stilbene oxide and 2. cEHCSO, epoxide hydrolase with diagnostic substrate specificity for cis-stilbene oxide | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cis-stilbene oxide + H2O | - |
Homo sapiens | ? | - |
? | |
cis-stilbene oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
styrene oxide + H2O | - |
Homo sapiens | styrene glycol | - |
? | |
styrene oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? | |
trans-stilbene oxide + H2O | - |
Homo sapiens | ? | - |
? | |
trans-stilbene oxide + H2O | - |
Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 49000, SDS-PAGE | Homo sapiens |
? | x * 49000, SDS-PAGE | Rattus norvegicus |
dimer | 2 * 60000, SDS-PAGE | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
cytosolic enzyme | Homo sapiens |
7.4 | - |
cytosolic enzyme | Rattus norvegicus |
9 | - |
- |
Rattus norvegicus |
9 | - |
microsomal enzyme | Homo sapiens |