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Literature summary for 3.3.2.10 extracted from

  • Hammock, B.D.; Prestwich, G.D.; Loury, D.N.; Cheung, P.Y.K.; Eng, W.S.; Park, S.K.; Moody, D.E.; Silva, M.H.; Wixtrom, R.N.
    Comparison of crude and affinity purified cytosolic epoxide hydrolases from hepatic tissue of control and clofibrate-fed mice (1986), Arch. Biochem. Biophys., 244, 292-309.
    View publication on PubMed
Search for more literature for 3.3.2.10

Activating Compound

Activating Compound Comment Organism Structure
Chalcone oxide substituted chalcone oxides, potent reversible inhibitors Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
4'-azidochalcone oxide
-
 Mus musculus
4'-phenylchalcone oxide
-
 Mus musculus
4-azidochalcone oxide
-
 Mus musculus
4-fluorochalcone oxide
-
 Mus musculus
4-Phenylchalcone oxide
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 gel filtration Mus musculus
59000
-
 1 * 59000, monomeric and dimeric enzyme forms retain catalytic activity, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 untreated and clofibrate-treated animals
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzopyrene 4,5-oxide + H2O
-
 Mus musculus (-)benzopyrene 4,5-dihydrodiol
-
 ?
cis-stilbene oxide + H2O
-
 Mus musculus ?
-
 ?
trans-stilbene oxide + H2O
-
 Mus musculus ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 59000, monomeric and dimeric enzyme forms retain catalytic activity, SDS-PAGE Mus musculus