Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
cytosol | - |
Rattus norvegicus | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
x * 50000, SDS-PAGE | Rattus norvegicus |
58000 | - |
gel filtration, monomeric or dimeric enzyme, dependent on conditions | Homo sapiens |
140000 | - |
gel filtration, monomeric or dimeric enzyme, dependent on conditions | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
425fold from liver cytosol to homogeneity by ammonium sulfate fractionation, cellulose resin, hydroxylapaptite, and ion exchange chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
substrate specificity | Rattus norvegicus |
additional information | - |
substrate specificity, 2 enzymes with different specificities termed cytosolic TESO hydrolase and cytosolic PNSO hydrolase | Homo sapiens |
0.0078 | - |
purified enzyme, substrate 4-nitrostyrene 7,8-oxide | Homo sapiens |
0.051 | - |
purified enzyme, substrate trans-8-ethylstyrene 7,8-oxide | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrostyrene 7,8-oxide + H2O | i.e. PNSO | Homo sapiens | ? | - |
? | |
4-nitrostyrene 7,8-oxide + H2O | i.e. PNSO | Rattus norvegicus | ? | - |
? | |
cis-8-ethylstyrene 7,8-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
cis-8-ethylstyrene 7,8-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
additional information | substrate specificity, 2 enzymes with different specificities termed cytosolic TESO hydrolase and cytosolic PNSO hydrolase, no activity with benz[a]pyrene 4,5-oxide | Homo sapiens | ? | - |
? | |
additional information | substrate specificity, no activity with benz[a]pyrene 4,5-oxide | Rattus norvegicus | ? | - |
? | |
naphthalene 1,2-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
naphthalene 1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
styrene 7,8-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
styrene 7,8-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
trans-8-ethylstyrene 7,8-oxide + H2O | i.e. TESO | Homo sapiens | ? | - |
? | |
trans-8-ethylstyrene 7,8-oxide + H2O | i.e. TESO | Rattus norvegicus | ? | - |
? | |
trans-stilbene oxide + H2O | - |
Homo sapiens | ? | - |
? | |
trans-stilbene oxide + H2O | - |
Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, SDS-PAGE | Rattus norvegicus |
monomer or dimer | n * 58000, SDS-PAGE | Homo sapiens |
More | peptide mapping | Homo sapiens |
More | peptide mapping | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
PNSO hydrolase | - |
Homo sapiens |
TESO hydrolase | - |
Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | isoelectric focusing | 6.1 | 5.1 |