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Literature summary for 3.2.2.6 extracted from

  • Coskun, O.; Nurten, R.
    Purification of NAD+ glycohydrolase from human serum (2013), Oncol. Lett., 6, 227-231.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.6

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular surface antigen CD38 Homo sapiens
-
-
soluble
-
 Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 gel filtration Homo sapiens
39000
-
 1 * 39000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cyclic ADP-ribose + H2O Homo sapiens
-
 ADP-D-ribose
-
 ?
NAD+ Homo sapiens
-
 cyclic ADP-ribose + nicotinamide
-
 ?
NAD+ + H2O Homo sapiens overall reaction ADP-D-ribose + nicotinamide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P28907
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme 480fold from serum by ammonium sulfate fractionation, affinity chromatography, gel filtration, and isoelectric focusing, and again gel filtration, to homogeneity Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood serum surface antigen CD38 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclic ADP-ribose + H2O
-
 Homo sapiens ADP-D-ribose
-
 ?
NAD+
-
 Homo sapiens cyclic ADP-ribose + nicotinamide
-
 ?
NAD+ + H2O overall reaction Homo sapiens ADP-D-ribose + nicotinamide
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 39000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
CD38
-
 Homo sapiens
NAD+ glycohydrolase
-
 Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens isoelectric focusing 6.6 6.4