Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cyclic ADP-ribose + H2O | - |
Mus musculus | ADP-ribose | - |
? | |
NAD+ + H2O | the cyclization and hydrolysis of NAD(P)+ occur optimally at physiological pH | Mus musculus | cyclic ADP-ribose + nicotinamide + H+ | - |
? | |
NADP+ + nicotinic acid | this reaction occurs only in acidic pH | Mus musculus | nicotinic acid adenine dinucleotide phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CD38 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | CD38 knockout mice manifest multiple defects relating to Ca2+ signaling, including that of insulin secretion, hormonal signaling in pancreatic acinar cells, migration of dendritic cell precursors, bone resorption, airway responsiveness, alpha-adrenoceptor signaling in aorta, cardiac hypertrophy, susceptibility to bacterial infection, as well as social behavior in mice through modulation of oxytocin secretion | Mus musculus |