Cloned (Comment) | Organism |
---|---|
expressed in Pichia pastoris | Schistosoma mansoni |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cyanidin | - |
Schistosoma mansoni | |
delphinidin | - |
Schistosoma mansoni | |
diosmetinidin | - |
Schistosoma mansoni | |
fisetinidin | - |
Schistosoma mansoni | |
kuromanin | - |
Schistosoma mansoni | |
luteolin | - |
Schistosoma mansoni | |
luteolinidin | - |
Schistosoma mansoni | |
malvidin | - |
Schistosoma mansoni | |
additional information | not inhibited by rac-catechin, piceatannol, trans-resveratrol, praziquantel, cucurmin, chloroquine, mefloquine, Cibacron Blue 3GA, PJ-34, and 1,8-naphthalimide | Schistosoma mansoni | |
myricetin | - |
Schistosoma mansoni | |
pelargonidin | - |
Schistosoma mansoni | |
peonidin | - |
Schistosoma mansoni | |
petunidin | - |
Schistosoma mansoni | |
quercetagetin | - |
Schistosoma mansoni | |
quercetagetinidin | - |
Schistosoma mansoni | |
quercetin | - |
Schistosoma mansoni | |
rac-taxifolin | - |
Schistosoma mansoni | |
robinetin | - |
Schistosoma mansoni |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schistosoma mansoni | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Blue Sepharose column chromatography, gel filtration | Schistosoma mansoni |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
integument | - |
Schistosoma mansoni | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,N6-etheno NAD+ + H2O | - |
Schistosoma mansoni | epsilon-ADP-ribose + nicotinamide + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NACE | - |
Schistosoma mansoni |
NAD+ catabolizing enzyme | - |
Schistosoma mansoni |
NAD+glycohydrolase | - |
Schistosoma mansoni |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0013 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | quercetagetin | |
0.0023 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | cyanidin | |
0.0039 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | quercetin | |
0.0044 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | pelargonidin | |
0.0056 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | peonidin | |
0.0058 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | robinetin | |
0.0059 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | luteolinidin | |
0.006 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | delphinidin | |
0.0061 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | quercetagetinidin | |
0.0064 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | fisetinidin | |
0.008 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | malvidin | |
0.0082 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | kuromanin | |
0.0084 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | luteolin | |
0.0099 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | diosmetinidin | |
0.0195 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | rac-taxifolin | |
0.022 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | myricetin | |
0.0378 | - |
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogen | Schistosoma mansoni | petunidin |