Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.2.5 extracted from

  • Ghosh, J.; Caparon, M.G.
    Specificity of Streptococcus pyogenes NAD(+) glycohydrolase in cytolysin-mediated translocation (2006), Mol. Microbiol., 62, 1203-1214.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
DELTA41-140 166% of wild-type activity, loss of translocation competence Streptococcus pyogenes
DELTA41-190 221% of wild-type activity, loss of translocation competence Streptococcus pyogenes
DELTA41-240 3.5% of wild-type activity, loss of translocation competence Streptococcus pyogenes
DELTA41-90 212% of wild-type activity, less stable than wild-type Streptococcus pyogenes

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
-
-

Subunits

Subunits Comment Organism
More enzyme contains an amino-terminal domain that is not required for enzymatic activity, but involved in its translocation Streptococcus pyogenes