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Literature summary for 3.2.2.5 extracted from
- Purification and characterization of NAD glycohydrolase from rabbit erythrocytes (1993), Arch. Biochem. Biophys., 305, 147-152.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ADPribose | - |
Oryctolagus cuniculus |  |
| isoniazid | - |
Oryctolagus cuniculus | |
| nicotinamide | - |
Oryctolagus cuniculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.043 | - |
NAD+ | - |
Oryctolagus cuniculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 63000 | - |
gel filtration | Oryctolagus cuniculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + H2O | Oryctolagus cuniculus | - |
ADPribose + nicotinamide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Oryctolagus cuniculus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Oryctolagus cuniculus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, 6 months, phosphate buffer, 30%, w/v glycerol | Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-acetylpyridine hypoxanthine dinucleotide + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| NAD+ + H2O | - |
Oryctolagus cuniculus | ADPribose + nicotinamide | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
10 min, loss of 50% of activity | Oryctolagus cuniculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
broad pH-optimum | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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