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Literature summary for 3.2.2.5 extracted from

  • Nakazawa, K.; Ueda, K.; Honjo, T.; Yoshihara, K.; Nishizuka, Y.; Hayaishi, O.
    Nicotinamide adenine dinucleotide glycohydrolases and poly adenosine diphosphate ribose synthesis in rat liver (1968), Biochem. Biophys. Res. Commun., 32, 143-194.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
3-acetylpyridine
-
 Rattus norvegicus
nicotinamide
-
 Rattus norvegicus
thioNAD+
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-
nucleus
-
 Rattus norvegicus 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NAD+ + H2O Rattus norvegicus
-
 ADPribose + nicotinamide
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + H2O
-
 Rattus norvegicus ADPribose + nicotinamide
-
 ?
NADP+ + H2O
-
 Rattus norvegicus phospho-ADPribose + nicotinamide
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.4
-
-
 Rattus norvegicus
7.6 8 chromatin NADase Rattus norvegicus