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Literature summary for 3.2.2.26 extracted from

  • Hiratsuka, T.; Furihata, K.; Ishikawa, J.; Yamashita, H.; Itoh, N.; Seto, H.; Dairi, T.
    An alternative menaquinone biosynthetic pathway operating in microorganisms (2008), Science, 321, 1670-1673.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Thermus thermophilus
-
Streptomyces coelicolor

Protein Variants

Protein Variants Comment Organism
additional information strain lacking the activity accumulates futalosine. Recombinant expression does not result in an active enzyme Streptomyces coelicolor

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor Q9KXN0
-
-
Thermus thermophilus Q5SKT7
-
-
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 Q5SKT7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
futalosine + H2O
-
Thermus thermophilus dehypoxanthine futalosine + hypoxanthine
-
?
futalosine + H2O
-
Streptomyces coelicolor dehypoxanthine futalosine + hypoxanthine
-
?
futalosine + H2O
-
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 dehypoxanthine futalosine + hypoxanthine
-
?