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Literature summary for 3.2.2.23 extracted from

  • Koval, V.V.; Kuznetsov, N.A.; Zharkov, D.O.; Ishchenko, A.A.; Douglas, K.T.; Nevinsky, G.A.; Fedorova, O.S.
    Pre-steady-state kinetics shows differences in processing of various DNA lesions by Escherichia coli formamidopyrimidine-DNA glycosylase (2004), Nucleic Acids Res., 32, 926-935.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.23

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Reaction

Reaction Comment Organism Reaction ID
DNA containing ring-opened N7-methylguanine + H2O = deguanylated DNA + 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine several fast sequential conformational changes occur in enzyme after binding to its substrate, converting the protein into a catalytically active conformation Escherichia coli
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oligonucleotide containing 8-oxo-2'-deoxyguanosine residue + H2O
-
 Escherichia coli oligonucleotide + 8-oxo-2'-deoxyguanosine
-
 ?
oligonucleotide containing abasic site residue + H2O
-
 Escherichia coli oligonucleotide + abasic site
-
 ?
oligonucleotide containing tetrahydrofuran residue + H2O
-
 Escherichia coli oligonucleotide + tetrahydrofuran
-
 ?