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Literature summary for 3.2.2.22 extracted from

  • Horrix, C.; Raviv, Z.; Flescher, E.; Voss, C.; Berger, M.
    Plant ribosome-inactivating proteins type II induce the unfolded protein response in human cancer cells (2011), Cell. Mol. Life Sci., 68, 1269-1281.
    View publication on PubMed
Search for more literature for 3.2.2.22

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
28S rRNA + H2O Ricinus communis depurination of a specific adenine in 28S rRNA apurinic 28S rRNA + adenine
-
 ?
28S rRNA + H2O Ximenia americana depurination of a specific adenine in 28S rRNA apurinic 28S rRNA + adenine
-
 ?
28S rRNA + H2O Adenia volkensii depurination of a specific adenine in 28S rRNA apurinic 28S rRNA + adenine
-
 ?

Organism

Organism UniProt Comment Textmining
Adenia volkensii
-
-
-
Ricinus communis
-
-
-
Ximenia americana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
28S rRNA + H2O depurination of a specific adenine in 28S rRNA Ricinus communis apurinic 28S rRNA + adenine
-
 ?
28S rRNA + H2O depurination of a specific adenine in 28S rRNA Ximenia americana apurinic 28S rRNA + adenine
-
 ?
28S rRNA + H2O depurination of a specific adenine in 28S rRNA Adenia volkensii apurinic 28S rRNA + adenine
-
 ?

Synonyms

Synonyms Comment Organism
ribosome-inactivating protein type II
-
 Ricinus communis
ribosome-inactivating protein type II
-
 Ximenia americana
ribosome-inactivating protein type II
-
 Adenia volkensii
ricin
-
 Ricinus communis
RIP
-
 Ricinus communis
RIP
-
 Ximenia americana
RIP
-
 Adenia volkensii
riproximin
-
 Ximenia americana
volkensin
-
 Adenia volkensii

General Information

General Information Comment Organism
physiological function ricin induces the expression of unfolded protein response genes, the (protein kinase RNA-activated)-like endoplasmic reticulum kinase branch of the unfolded protein response, and activates the activating transcription factor 6 pathway of the unfolded protein response, but not the inositol-requiring protein 1 branch Ricinus communis
physiological function riproximin induces the (protein kinase RNA-activated)-like endoplasmic reticulum kinase branch of the unfolded protein response and activates the activating transcription factor 6 pathway of the unfolded protein response, but not the inositol-requiring protein 1 branch Ximenia americana
physiological function volkensin induces the (protein kinase RNA-activated)-like endoplasmic reticulum kinase branch of the unfolded protein response, and activates the activating transcription factor 6 pathway of the unfolded protein response, but not the inositol-requiring protein 1 branch Adenia volkensii