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Literature summary for 3.2.2.22 extracted from
- Oropharyngeal aspiration of ricin as a lung challenge model for evaluation of the therapeutic index of antibodies against ricin A-chain for post-exposure treatment (2007), Exp. Lung Res., 33, 459-481.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | development of an oropharyngeal aspiration model for ricin lethal challenge and antibody administration. When polyclonal anti-deglycosylated ricin A chain antibody is administered between 1-18 h after ricin challenge, all mice survive, while delayed treatment to 24 h results in 30% survival. Protective effects of antibody correlate with inhibition of apoptosis in lungs in vivo and in RAW264.7 macrophage and Jurkat cells in vitro | Ricinus communis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ricinus communis | - |
- |
- |
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Release 2023.1 (January 2023)
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