Literature summary for 3.2.2.22 extracted from

Wang, H.B.; Xia, F.; Ge, J.; Yin, J.; Tan, L.S.; Zhang, P.D.; Zhong, J.
Co-application of ricin A chain and a recombinant adenovirus expressing ricin B chain as a novel approach for cancer therapy (2007), Acta Pharmacol. Sin., 28, 657-662.

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Application

Application	Comment	Organism
medicine	expression of A chain in Escherichia coli with His-tag and purification. Construction of replication-deficient ricin B chain adenovirus-green fluorescent protein fusion protein. When used individually, neither A chain nor B chain protein is toxic to human cell lines HEK 293, HeLa, SMMC 7721, and HL 7702, and entry of A chain into cells infected with the fusion contruct is confirmed. When applied together, significant cell death is observed in all cell lines tested	Ricinus communis

Cloned(Commentary)

Cloned (Comment)	Organism
expression of A chain in Escherichia coli with His-tag. Construction of replication-deficient ricin B chain adenovirus-green fluorescent protein fusion protein	Ricinus communis

Organism

Organism	UniProt	Comment	Textmining
Ricinus communis	-	-	-

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Release 2023.1 (January 2023)