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Literature summary for 3.2.2.22 extracted from

  • Barbieri, L.; Valbonesi, P.; Righi, F.; Zuccheri, G.; Monti, F.; Gorini, P.; Samori, B.; Stirpe, F.
    Polynucleotide:Adenosine glycosidase is the sole activity of ribosome-inactivating proteins on DNA (2000), J. Biochem., 128, 883-889.
    View publication on PubMed
Search for more literature for 3.2.2.22

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
rRNA + H2O Saponaria officinalis
-
 ?
-
 ?
rRNA + H2O Phytolacca americana
-
 ?
-
 ?
rRNA + H2O Suregada multiflora
-
 ?
-
 ?
rRNA + H2O Momordica charantia
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Momordica charantia
-
-
-
Phytolacca americana
-
 pokeweed, enzyme forms: PAP, PAP II, PAP-S
-
Saponaria officinalis
-
-
-
Suregada multiflora
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saponaria officinalis
-
 Phytolacca americana
-
 Suregada multiflora
-
 Momordica charantia

Source Tissue

Source Tissue Comment Organism Textmining
seed
-
 Saponaria officinalis
-
seed
-
 Phytolacca americana
-
seed
-
 Suregada multiflora
-
seed
-
 Momordica charantia
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
rRNA + H2O
-
 Saponaria officinalis ?
-
 ?
rRNA + H2O
-
 Phytolacca americana ?
-
 ?
rRNA + H2O
-
 Suregada multiflora ?
-
 ?
rRNA + H2O
-
 Momordica charantia ?
-
 ?
supercoiled double-stranded DNA + H2O highly purified enzymes depurinate extensively pBR322 circular, supercoiled DNA at neutral pH and exhibit neither DNase nor DNA glycosylase activities, DNA modifications other than depurination may be attributed to contamination with nucleases, gelonin, momordin I, PAP-S, and saporin-S6 do not cleave DNA strands, the only base released is adenine, it may be concluded that polynucleotide:adenosine glycosidase is the enzymatic activity on DNA of these, and possibly all, ribosome-inactivating proteins Saponaria officinalis nicked and linear forms of DNA
-
 ?
supercoiled double-stranded DNA + H2O highly purified enzymes depurinate extensively pBR322 circular, supercoiled DNA at neutral pH and exhibit neither DNase nor DNA glycosylase activities, DNA modifications other than depurination may be attributed to contamination with nucleases, gelonin, momordin I, PAP-S, and saporin-S6 do not cleave DNA strands, the only base released is adenine, it may be concluded that polynucleotide:adenosine glycosidase is the enzymatic activity on DNA of these, and possibly all, ribosome-inactivating proteins Phytolacca americana nicked and linear forms of DNA
-
 ?
supercoiled double-stranded DNA + H2O highly purified enzymes depurinate extensively pBR322 circular, supercoiled DNA at neutral pH and exhibit neither DNase nor DNA glycosylase activities, DNA modifications other than depurination may be attributed to contamination with nucleases, gelonin, momordin I, PAP-S, and saporin-S6 do not cleave DNA strands, the only base released is adenine, it may be concluded that polynucleotide:adenosine glycosidase is the enzymatic activity on DNA of these, and possibly all, ribosome-inactivating proteins Suregada multiflora nicked and linear forms of DNA
-
 ?
supercoiled double-stranded DNA + H2O highly purified enzymes depurinate extensively pBR322 circular, supercoiled DNA at neutral pH and exhibit neither DNase nor DNA glycosylase activities, DNA modifications other than depurination may be attributed to contamination with nucleases, gelonin, momordin I, PAP-S, and saporin-S6 do not cleave DNA strands, the only base released is adenine, it may be concluded that polynucleotide:adenosine glycosidase is the enzymatic activity on DNA of these, and possibly all, ribosome-inactivating proteins Momordica charantia nicked and linear forms of DNA
-
 ?

Synonyms

Synonyms Comment Organism
momordin
-
 Momordica charantia
momordin I
-
 Momordica charantia
PAP-S
-
 Phytolacca americana
saporin-6
-
 Saponaria officinalis