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Literature summary for 3.2.2.20 extracted from
- A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD (2006), Mol. Microbiol., 59, 1602-1609.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli BL2, AlkC | Bacillus cereus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 28000 | - |
x * 28000, AlkC, SDS-PAGE | Bacillus cereus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Bacillus cereus | AlkC is involved exclusively in the repair of alkylation damage | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus cereus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bacillus cereus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | AlkC is specific for 3-methylpurines | Bacillus cereus | 3-methyladenine + 3-methylguanine + ? | - |
? | |
| additional information | AlkC is involved exclusively in the repair of alkylation damage | Bacillus cereus | ? | - |
? | |
| additional information | no detectable affinity for hypoxanthine, 8-oxoguanine and 5-formyluracil | Bacillus cereus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 28000, AlkC, SDS-PAGE | Bacillus cereus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AlkC | - |
Bacillus cereus |
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Release 2023.1 (January 2023)
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