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Literature summary for 3.2.2.20 extracted from
- A novel zinc snap motif conveys structural stability to 3-methyladenine DNA glycosylase I (2003), J. Biol. Chem., 278, 19442-19446.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| wild-type TAG overexpressed from pET21a(TAG) in Escherichia coli BL21(DE3) | Escherichia coli |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | binds Zn2+ extremely tight to stabilize the HhH domain | Escherichia coli |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | Escherichia coli | smallest member of the helix-hairpin-helix HhH superfamily of DNA glycosylases | 3-methyladenine + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P05100 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | - |
Escherichia coli | 3-methyladenine + ? | - |
? | |
| alkylated DNA + H2O | smallest member of the helix-hairpin-helix HhH superfamily of DNA glycosylases | Escherichia coli | 3-methyladenine + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TAG | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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