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Literature summary for 3.2.2.20 extracted from
- Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents (1992), EMBO J., 11, 4439-4444.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| integration and expression of the tag gene with retroviral vectors into chinese hamster V79 cells by liposome mediated transfection and into murine haemopoeitic stemm cells by cocultivation with a lipofected, virus-packaging cell line, stable transfectants are more resistant to cytotoxic effects of methylmethanesulfonate and N-methyl-nitrosourea than their parent cell lines | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | Escherichia coli | - |
3-methyladenine + ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | - |
Escherichia coli | 3-methyladenine + ? | - |
? | |
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