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Literature summary for 3.2.2.17 extracted from

  • Meador, M.G.; Rajagopalan, L.; Lloyd, R.S.; Dodson, M.L.
    Role of His-16 in turnover of T4 pyrimidine dimer glycosylase (2004), J. Biol. Chem., 279, 3348-3353.
    View publication on PubMed
Search for more literature for 3.2.2.17

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli of several mutants Escherichia coli

Protein Variants

Protein Variants Comment Organism
H16A performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
H16A decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
H16C performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
H16C decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
H16D performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
H16D decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
H16E performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
H16E decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
H16K performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
H16K decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
H16S performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
H16S decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Tequatrovirus T4
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, using several chromatographic steps Escherichia coli

Reaction

Reaction Comment Organism Reaction ID
thymidine-dimer-containing DNA + H2O = thymidine-dimer-containing DNA with apyrimidinic site scheme of reaction mechanism Tequatrovirus T4
a

Synonyms

Synonyms Comment Organism
pyrimidine dimer glycosylase
-
 Tequatrovirus T4
T4-PDG
-
 Tequatrovirus T4